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[[File:Medici Three.jpg|thumbnail|left|300px250px|Cosimo De Medici]]
What were the contributions of the de Medici family to the Renaissance in Italy during the fifteenth century? The de Medicis were the effective rulers of the Florentine Republic in the 15th century, and they later became the ruling house of Florence in the 16th and 17th century. The family, especially in the fifteenth century made a decisive contribution to the Renaissance in Italy.