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For most of the third and second centuries BC, the Seleucid Empire was the greatest of Alexander the Great’s Hellenistic successor states. Stretching from boundary of Persia to the Mediterranean Sea, and at times including parts of Anatolia, the Seleucid Empire was the largest of all the successor states, but it was also among the most culturally and politically important as well. The Seleucid Dynasty was headquartered in the newly built city of Seleucia and was in many ways the inheritor of ancient Mesopotamian culture as well as the torch bearer of Greek culture in the east, bringing the ideas of Hellenism to Mesopotamia but also allowing the natives to practice their ancient religion. Eventually, though, the greatness that was the Seleucid Empire came to a quick and violent end.