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At the battle of Gaugamela, he wrecked Darius's army and proceded to annex all of Persia. The Macedonian monarch pursued Darius II into Central Asia, but failed to capture him before he was assassinated by one of his generals. Alexander’s conquests provided a great administrative challenge, and he adopted the Persian system of satrapies or semi-autonomous territorial units, which were ruled by his Macedonian lieutenant. He also chose a conciliatory policy towards the Persians, as evidenced by his treatment of the family of Darius.<ref> Plutarch. Life of Alexander, v, ix</ref>
Alexander alienated many of his generals by his actions. In particular, they disliked the fact that he began to assume the prerogatives and manners of an Oriental monarch and was introducing Persians into the army.<ref> Arrian, 4, 67</ref> The conqueror was not content with his vast domains and wanted to conquer the known world. He invaded north-west India and successfully annexed several kingdoms before his troops mutinied and forced him to turn back. The retreat from India was a disaster, and many died crossing the Gederosian Desert. Alexander returned to Babylon, but he soon developed a fever and fell gravely ill and died at the age of 32 in 322 323 BC.
====Civil War and Disintegration====